Fig. 1
Experimental design and effects of curcumin on body weight of mice. A Schematic representation of the experimental design. Mice were adapted for 3 days before the onset of hypoxia (13%O2) stress. Subsequently, mice were subjected to a 2-weeks hypoxia stress followed by behavioral tests. B Initial body weight. There was no significant difference in initial body weight among each group mice. C Effects of curcumin on mice weight. Mice subjected to hypoxia stress exhibited reduced body weight compared with the control group, and 300 mg curcumin had negative effect on mice body weight. Con = control group; H14d = mice treated with 13% O2 for 14 days group; cur-1/2/3 = curcumin (100, 200, and 300 mg/kg) groups; H14d + Cur-1/2/3 = H14d + curcumin (100, 200, and 300 mg/kg) groups. All data are expressed as mean ± SEM, n = 6, *p < 0.05, **p < 0.01 versus Con group, #p < 0.05, ##p < 0.01 versus H14d group.
