Table 2 Assessment of heterogeneity and directional pleiotropy.

From: Genetic association between immune-mediated inflammatory diseases and peripheral artery disease: a Mendelian randomization study

Exposure

Heterogeneity

MR-Egger

MR-PRESSO

Q

Q-pval

Intercept

SE

p

Global test-pval

RA

82.590

0.311

-0.006

0.004

0.163

0.272

UC

68.634

0.021

-0.012

0.013

0.362

0.228

CD

83.992

0.178

0.005

0.007

0.536

0.069

SLE

31.728

0.754

-0.010

0.009

0.289

0.650

AS

3.113

0.539

0.025

0.017

0.217

0.553

PSO

21.671

0.301

0.001

0.007

0.852

0.351

MS

26.240

0.094

0.003

0.018

0.872

0.085

HT

17.736

0.023

0.004

0.028

0.882

0.431

  1. Q heterogeneity statistic Q, SE standard error, RA rheumatoid arthritis, UC ulcerative colitis, CD Crohn’s disease, SLE systemic lupus erythematosus, AS ankylosing spondylitis, PSO psoriasis, MS multiple sclerosis, HT hashimoto thyroiditis.
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