Table 4 Associations between combined CT-based muscle abnormalities and mortality at 12, 24, and 36 months in patients with colorectal cancer.

From: Impact of body composition and muscle health phenotypes on survival outcomes in colorectal cancer: a multicenter cohort

Variables

HRadjusted

95% CI

P

SMI + SMD phenotype

12-month mortality

Normal SMI + Normal SMD

(Reference)

  

Normal SMI + Low SMD

1.60

0.88 to 2.91

0.12

Low SMI + Normal SMD

2.08

1.14 to 3.80

0.018

Low SMI + Low SMD

3.10

1.78 to 5.41

< 0.001

24-month mortality

Normal SMI + Normal SMD

(Reference)

  

Normal SMI + Low SMD

1.45

0.93 to 2.34

0.10

Low SMI + Normal SMD

1.88

1.21 to 2.96

0.005

Low SMI + Low SMD

2.06

1.31 to 3.24

0.002

36-month mortality

Normal SMI + Normal SMD

(Reference)

  

Normal SMI + Low SMD

1.03

0.70 to 1.50

0.89

Low SMI + Normal SMD

1.57

1.09 to 2.28

0.017

Low SMI + Low SMD

1.55

1.05 to 2.30

0.028

  1. Cox regression analysis. HR: hazard ratio; 95% CI: 95% confidence interval.
  2. Models were sex-stratified and adjusted for age, sex, metastasis at diagnosis, Charlson comorbidity index, and body mass index.
  3. CT, computed tomography; SMD, skeletal muscle; SMI, skeletal muscle index.
  4. Significant values are in bold.
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