Fig. 12 | Scientific Reports

Fig. 12

From: Integrating immune multi-omics and machine learning to improve prognosis, immune landscape, and sensitivity to first- and second-line treatments for head and neck squamous cell carcinoma

Fig. 12

Evaluation of radiotherapy, chemotherapy, and EGFR-targeted therapy responses. (A) Two radiotherapy-related biomarkers (hypoxia and cell cycle) were significantly enriched in the high CMPIS patients. (B) Three commonly used chemotherapeutic drugs (Cisplatin, 5-Fluorouracil, and Gemcitabine) were more sensitive in the low CMPIS patients. (C) EGFR ligand scores were higher in the high CMPIS patients, and the three EGFR-targeted therapeutic agents were more sensitive in the high CMPIS patients.

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