Table 3 The relationship between clinical parameters and the NOS3 genotype.

From: Association of endothelial nitric oxide synthase (NOS3) rs2070744 variant with advanced retinopathy of prematurity: a case–control study and meta-analysis

Parameter

rs2070744

rs1799983

TT + TC

CC

P

GG + GT

TT

P

Gestational age [wk.]

27.6 (2.2)

28.1 (1.9)

0.166

27.6 (2.2)

27.9 (2.2)

0.580

Body weight [g]

1098.5 (342.3)

1158.4 (344.3)

0.279

1107.7 (342.5)

1095.0 (346.8)

0.865

Sex, % of males

54.0

60.9

0.389

54.0

65.2

0.301

No. of RBC transfusions Mean (SD)

4.7 (3.5)

3.1 (3.4)

0.017

4.6 (3.6)

2.5 (2.1)

0.033

RBC transfusions [ml]

101.0 (68.6)

77.9 (95.3)

0.217

100.2 (73.3)

48.2 (46.6)

0.089

Mech. vent. time period [d]; Mean (SD)

24.9 (26.1)

21.6 (24.4)

0.433

24.1 (25.7)

28.5 (28.0)

0.447

ROP max stage Med (Q1, Q3)

2 (0, 3)

1.5 (0, 3)

0.089

2 (0, 3)

3 (0, 3)

0.747

Complications of prematurity; (%)

NEC

26.8

23.9

0.686

25.3

39.1

0.149

BPD

40.2

43.5

0.676

40.6

43.5

0.789

IVH

59.8

56.5

0.676

59.4

60.9

0.899

RDS

72.8

56.5

0.027

69.7

78.3

0.390

DWMI

8.4

4.4

0.349

8.1

4.4

0.525

Sepsis

31.5

5.9

0.002

27.7

15.4

0.334