Table 3 The relationship between clinical parameters and the NOS3 genotype.
Parameter | rs2070744 | rs1799983 | ||||
---|---|---|---|---|---|---|
TT + TC | CC | P | GG + GT | TT | P | |
Gestational age [wk.] | 27.6 (2.2) | 28.1 (1.9) | 0.166 | 27.6 (2.2) | 27.9 (2.2) | 0.580 |
Body weight [g] | 1098.5 (342.3) | 1158.4 (344.3) | 0.279 | 1107.7 (342.5) | 1095.0 (346.8) | 0.865 |
Sex, % of males | 54.0 | 60.9 | 0.389 | 54.0 | 65.2 | 0.301 |
No. of RBC transfusions Mean (SD) | 4.7 (3.5) | 3.1 (3.4) | 0.017 | 4.6 (3.6) | 2.5 (2.1) | 0.033 |
RBC transfusions [ml] | 101.0 (68.6) | 77.9 (95.3) | 0.217 | 100.2 (73.3) | 48.2 (46.6) | 0.089 |
Mech. vent. time period [d]; Mean (SD) | 24.9 (26.1) | 21.6 (24.4) | 0.433 | 24.1 (25.7) | 28.5 (28.0) | 0.447 |
ROP max stage Med (Q1, Q3) | 2 (0, 3) | 1.5 (0, 3) | 0.089 | 2 (0, 3) | 3 (0, 3) | 0.747 |
Complications of prematurity; (%) | ||||||
NEC | 26.8 | 23.9 | 0.686 | 25.3 | 39.1 | 0.149 |
BPD | 40.2 | 43.5 | 0.676 | 40.6 | 43.5 | 0.789 |
IVH | 59.8 | 56.5 | 0.676 | 59.4 | 60.9 | 0.899 |
RDS | 72.8 | 56.5 | 0.027 | 69.7 | 78.3 | 0.390 |
DWMI | 8.4 | 4.4 | 0.349 | 8.1 | 4.4 | 0.525 |
Sepsis | 31.5 | 5.9 | 0.002 | 27.7 | 15.4 | 0.334 |