Table 6 Description of the four studied single nucleotide variants.
Gene symbol | Encoded protein | dbSNP ID number | Nucleotide substitution | Region (protein change) | TaqMan assay number |
|---|---|---|---|---|---|
NOS3 | Endothelial nitric oxide synthase | rs2070744 | − 786 C > T | Promoter region | C_15903863_10 |
rs1799983 | 894G > T | Exon 7 (Glu298Asp) | C_3219460_20 | ||
EDN1 | Endothelin 1 | rs5370 | 5665G > T | Exon 5 (Lys198Asn) | C_598677_1_ |
EDNRA | Endothelin receptor A | rs5335 | + 70G > C | 3′-UTR | C_8869366_20 |
