Fig. 4 | Scientific Reports

Fig. 4

From: Mendelian randomization analysis reveals causal effects of migraine and its subtypes on early-onset ischemic stroke risk

Fig. 4

Sensitivity analyses of migraine with aura on early-onset ischemic stroke. (A) Sensitivity analysis was conducted by exclusively relying on SNPs that exhibited low evidence of heterogeneity across different stroke cohorts (with I2 less than 50% and a p-value of the Q statistic greater than 0.05). (B) Sensitivity analysis was conducted using SNPs, without consideration of whether they were associated with potential confounders. Het_p indicates p-value of heterogeneity test. Ple_p indicates p-value of pleiotropy test. Abbreviations: SNP, single nucleotide polymorphism; IHGC, International Headache Genetics Consortium; OR, odds ratio; CI, confidence interval; MA, migraine with aura.

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