Table 1 Demographic and clinical characteristics of the study population.
From: Development and validation of a prognostic nomogram model for severe osteomyelitis patients
Survival (N = 1016) | Death (N = 137) | p | |
|---|---|---|---|
Age (years) | 64.2 [54.9;72.8] | 73.8 [65.1;81.7] | < 0.001 |
Gender | 0.866 | ||
Female | 390 (38.4%) | 51 (37.2%) | |
Male | 626 (61.6%) | 86 (62.8%) | |
BMI (kg/m2) | 28.9 [24.3;34.1] | 28.8 [24.3;34.7] | 0.849 |
Weight (kg) | 85.3 [69.8;103] | 80.1 [64.2;97.0] | 0.016 |
Race | 0.910 | ||
Other | 332 (32.7%) | 46 (33.6%) | |
The white race | 684 (67.3%) | 91 (66.4%) | |
Marital status | 0.023 | ||
No | 551 (54.2%) | 89 (65.0%) | |
Yes | 465 (45.8%) | 48 (35.0%) | |
Heart rate | 84.0 [75.0;96.0] | 87.0 [76.0;97.0] | 0.057 |
SBP | 117 [107;131] | 110 [103;121] | < 0.001 |
DBP | 61.0 [54.0;69.0] | 56.0 [51.0;64.0] | < 0.001 |
MBP | 76.0 [70.0;84.0] | 71.0 [66.0;79.0] | < 0.001 |
RR | 18.0 [16.0;21.0] | 19.0 [17.0;22.0] | 0.016 |
Temperature (℃) | 36.8 [36.6;37.1] | 36.7 [36.4;36.9] | < 0.001 |
Spo2 (%) | 97.0 [96.0;99.0] | 97.0 [96.0;99.0] | 0.337 |
Hypertension | < 0.001 | ||
No | 409 (40.3%) | 105 (76.6%) | |
Yes | 607 (59.7%) | 32 (23.4%) | |
Diabetes | 0.451 | ||
No | 341 (33.6%) | 51 (37.2%) | |
Yes | 675 (66.4%) | 86 (62.8%) | |
Aki-stage | 0.140 | ||
0 | 475 (46.8%) | 50 (36.5%) | |
1 | 277 (27.3%) | 44 (32.1%) | |
2 | 159 (15.6%) | 24 (17.5%) | |
3 | 105 (10.3%) | 19 (13.9%) | |
Copd | 0.532 | ||
No | 921 (90.6%) | 127 (92.7%) | |
Yes | 95 (9.35%) | 10 (7.30%) | |
Sepsis | 0.002 | ||
No | 260 (25.6%) | 18 (13.1%) | |
Yes | 756 (74.4%) | 119 (86.9%) | |
Pathogenic bacteria | 0.798 | ||
No | 33 (3.25%) | 5 (3.65%) | |
Yes | 983 (96.8%) | 132 (96.4%) | |
Antibiotic: | 0.620 | ||
Other | 35 (3.44%) | 6 (4.38%) | |
Vancomycin | 981 (96.6%) | 131 (95.6%) | |
Lactate (mmol/L) | 1.50 [1.10;2.10] | 1.60 [1.30;2.30] | 0.020 |
Hemoglobin (g/dL) | 12.1 [10.7;13.4] | 10.3 [8.70;11.9] | < 0.001 |
Creatinine (mg/dL) | 1.10 [0.80;1.70] | 1.50 [1.00;2.40] | < 0.001 |
WBC, 109/L | 8.50 [6.60;11.9] | 10.3 [6.90;13.8] | 0.005 |
Crp (mg/L) | 50.5 [11.8;123] | 110 [52.1;179] | < 0.001 |
ALT (IU/L) | 22.0 [15.0;34.0] | 20.0 [13.0;33.0] | 0.278 |
AST (IU/L) | 24.0 [18.0;37.0] | 29.0 [22.0;51.0] | < 0.001 |
ALP (IU/L) | 90.0 [69.0;119] | 105 [78.0;160] | < 0.001 |
Albumin (g/dL) | 3.60 [3.00;4.10] | 2.90 [2.40;3.40] | < 0.001 |
Ca (mg/dL) | 8.80 [8.30;9.30] | 8.60 [8.10;9.10] | 0.006 |
Cl (mmol/L) | 101 [98.0;104] | 100 [97.0;104] | 0.381 |
K (mmol/L) | 4.30 [3.90;4.70] | 4.40 [3.90;4.80] | 0.217 |
Na (mmol/L) | 138 [135;141] | 137 [134;141] | 0.289 |
Mg (mmol/L) | 2.00 [1.80;2.20] | 2.00 [1.80;2.30] | 0.076 |
PH | 7.38 [7.33;7.44] | 7.37 [7.31;7.43] | 0.080 |
RDW (%) | 14.1 [13.3;15.2] | 15.5 [14.5;17.2] | < 0.001 |
RDW2 | < 0.001 | ||
≧14.5% | 403 (39.7%) | 106 (77.4%) | |
< 14.5% | 613 (60.3%) | 31 (22.6%) | |
INR | 1.10 [1.00;1.30] | 1.30 [1.20;1.60] | < 0.001 |
Anion gap (mmol/L) | 15.0 [13.0;17.0] | 16.0 [13.0;19.0] | 0.017 |
Platelets, 109/L | 251 [193;320] | 200 [145;286] | < 0.001 |
Mortality 28-day | < 0.001 | ||
No | 1016 (100%) | 111 (81.0%) | |
Yes | 0 (0.00%) | 26 (19.0%) | |
Mortality 90-day | < 0.001 | ||
No | 1016 (100%) | 84 (61.3%) | |
Yes | 0 (0.00%) | 53 (38.7%) | |
Los_icu (days) | 2.37 [1.58;4.24] | 3.27 [2.02;8.23] | < 0.001 |