Table 3 Univariate and Multivariate analysis of factors associated with overall survival in NPC.

From: The IL-10/STAT3 Axis Nasopharyngeal Carcinoma Cancer stem cell and radio resistance

Variable

Univariate analysis

Multivariate analysis

Hazard ratio

95% CI

P-value

Hazard ratio

95% CI

P-value

Gender Male vs. Female

0.781

0.568

-

1.674

0.512

     

Age (years) > 60 vs.≤ 60

1.467

0.914

-

1.739

0.421

     

TNM stage III + IV vs. I + II

1.395

1.158

-

1.988

0.032

0.628

0.317

-

1.716

0.532

Distant metastasis Yes vs. No

1.458

1.131

-

2.048

0.023

1.471

0.833

-

1.976

0.295

EBV history > 5.00E + 02 vs. ≤ 5.00E + 02

0.658

0.422

-

1.777

0.386

     

Tumor Size (cm) > 4 vs. ≤4

1.303

1.066

-

1.875

0.027

1.341

0.996

-

0.264

0.377

lymphatic metastasis Yes vs. No

1.289

0.703

-

1.454

0.837

     

Serum IL-10 level High vs. Low

1.669

1.503

-

2.246

0.013

1.60

1.371

-

2.423

0.011

  1. P < 0.05 by Cox proportional hazards regression model.
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