Fig. 5 | Scientific Reports

Fig. 5

From: Klotho enhances stability of chronic kidney disease atherosclerotic plaques by inhibiting GRK2/PLC-β-mediated endoplasmic reticulum stress in macrophages via modulation of the ROS/SHP1 pathway

Fig. 5

Klotho enhances the stability of atherosclerotic plaques through ROS/SHP1 pathway inhibition, downregulating GRK2/PLC-β-mediated ER stress. A Protein bands and relative protein expression levels of Klotho, NOX2, p-SHP1, p-Src, p-PERK, p-GRK2, and p-PLCβ, as well as statistical analysis; B Protein bands and relative protein expression levels of NOX2, p-SHP1, p-GRK2, p-PLCβ, and p-PERK, as well as statistical analysis. GAPDH as the control protein. N = 3; **P < 0.01; nsP > 0.05.

Back to article page