Table 6 Logistic regression analysis of factors associated with high willingness (> 70%) to participate in clinical trials.
Variables | Univariable | Multivariable | |||||||
|---|---|---|---|---|---|---|---|---|---|
Model 1a | Model 2b | ||||||||
OR | 95% CI | p-value | OR | 95% CI | p-value | OR | 95% CI | p-value | |
Gender, Male | 1.81 | 1.18, 2.78 | 0.006 | 1.75 | 1.11, 2.75 | 0.015 | 1.61 | 0.97, 2.70 | 0.071 |
Employment status | |||||||||
Employed | 1.00 | Ref | Ref | 1.00 | Ref | Ref | 1.00 | Ref | Ref |
Unemployed | 0.57 | 0.36, 0.90 | 0.016 | 0.40 | 0.18, 0.89 | 0.026 | 0.37 | 0.15, 0.95 | 0.039 |
Retired | 1.02 | 0.55, 1.89 | 0.951 | 0.63 | 0.29, 1.38 | 0.244 | 0.56 | 0.23, 1.34 | 0.193 |
Monthly Income | |||||||||
< RM1200 | 1.00 | Ref | Ref | 1.00 | Ref | Ref | 1.00 | Ref | Ref |
RM1200–RM2999 | 0.97 | 0.53, 1.77 | 0.921 | 0.43 | 0.18, 1.01 | 0.054 | 0.52 | 0.19, 1.40 | 0.195 |
RM3000–RM4999 | 1.23 | 0.62, 2.47 | 0.557 | 0.49 | 0.19, 1.26 | 0.138 | 0.45 | 0.15, 1.33 | 0.146 |
≥ RM5000 | 2.45 | 1.28, 4.66 | 0.006 | 0.75 | 0.30, 1.89 | 0.545 | 0.78 | 0.27, 2.29 | 0.650 |
Prior clinical trial exposure | 2.44 | 1.59, 3.76 | < 0.001 | 1.23 | 0.69, 2.19 | 0.486 | 0.89 | 0.46, 1.72 | 0.739 |
Knowledge | 1.02 | 1.01, 1.02 | < 0.001 | 1.01 | 1.01, 1.02 | < 0.001 | 1.01 | 1.00, 1.02 | 0.069 |
Perceived benefits | 1.11 | 1.08, 1.14 | < 0.001 | NA | NA | NA | 1.10 | 1.06, 1.13 | < 0.001 |
Perceived risks | 0.96 | 0.95, 0.98 | < 0.001 | NA | NA | NA | 0.95 | 0.93, 0.96 | < 0.001 |
Confidence in clinical trial conducts | 1.07 | 1.05, 1.09 | < 0.001 | NA | NA | NA | 1.03 | 1.00, 1.05 | 0.024 |
Religious barriers | 0.98 | 0.97, 0.99 | 0.004 | NA | NA | NA | 0.99 | 0.98, 1.01 | 0.368 |
