Table 1 Characteristics of Household contacts and Index participants.

From: Association of Mycobacterium tuberculosis aerosolization and HIV coinfection in the index case with T cell responses in household contacts

Household contact (HHC) characteristics

Total (N = 230)

Female gender (n, %)

135 (58.7%)

HHC age, years (median, IQR)

14.9 (6.5, 32.0)

BMI, kg/m2 (median (IQR)

20 (16.6, 25.4)

MUAC, cm (median, IQR)††

23 (16.5, 27.5)

PLWH†††

8 (3.5%)

Alcohol use (N = 212)

19 (9.0%)

Smoking status (N = 212)

7 (3.3%)

Shared bedroom with index (N = 215)

144 (67.0%)

Previously treated for TB (N = 216)

11 (5.1%)

Positive QuantiFERON (QFT) result in HHC (N = 220)*

129 (58.6%)

Index TB participants with whom HHC resided

Total (N = 92)

 Female gender (n, %)

35 (41.2%)

 Index age, years (median, IQR) (N = 91)

31.1 (25.4, 41.5)

 BMI (N = 90)

19.5 (18.0, 22.2)

 MUAC, cm (N = 90)

23.5 (21.7, 25.7)

 PLWH (N = 91)

13 (14.3%)

 Lowest Ct value (median, IQR) (N = 82)

19.5 (16.7, 24.5)

 Xpert grade (n, %) (N = 91)

  Grade 1 (Trace)

10 (11.0%)

  Grade 2 (Very Low)

7 (7.7%)

  Grade 3 (Low)

19 (20.9%)

  Grade 4 (Medium)

32 (35.2%)

  Grade 5 (High)

23 (25.3%)

 Smear grade (n, %) (N = 91)

  Negative

18 (19.8%)

  Scanty

10 (11%)

  (+) 1

25 (27.5%)

  (+) 2

19 (20.9%)

  (+) 3

19 (20.9%)

 CAC+††††

11 (12%)

 TTD, days (median, IQR) (N = 82)†††††

6 (4, 11)

 CXR cavitary disease (N = 91)

55 (60.4%)

 CRP (median, IQR) (N = 88)

55.1 (14.9, 86.9)

 Number of contacts for each index participant (% of households)

  1 HHC

32 (34.8%)

  2 HHC

19 (20.7%)

  3 HHC

16 (17.4%)

  4 HHC

16 (17.4%)

  5 HHC

6 (6.5%)

  6 HHC

3 (3.3%)

 Index participants with at least one HHC having positive QFT result (n, %)

62 (67.4%)

  1. *6 HHC had Indeterminate QFT-Plus test results and 4 HHC had missing QFT-Plus test results. QFT positivity is based on the remaining 220; BMI, Body mass index, IQR, interquartile range ; ††MUAC, Mid-Upper Arm Circumference; †††PLWH, Person Living with HIV; ††††CAC+, Cough Aerosol Culture positive/ Mtb growth; †††††TTD, Time to detection of Mtb growth in liquid media; Not all participants had complete data, the total with complete data is indicated where it differs from 230 in HHC or 92 in index participants.