Fig. 4

Differentially expressed genes revealed that ALKBH5 is involved in tumor immunity. (A) Volcano plot of differentially expressed transcripts regulated by ALKBH5. (B) Heatmap of the top 10 positively regulated genes and the top 10 negatively regulated genes. (C) GSEA of transcripts from RNA-seq. (D) GO analysis of differentially expressed transcripts. (E) KEGG analysis of differentially expressed transcripts. (F) Volcano plot of differentially methylated transcripts regulated by ALKBH5. (G) Heatmap of the top 10 genes with hypermethylation and top 10 with hypomethylation. (H) GSEA of transcripts from m6A-seq. (I) GO analysis of differentially methylated transcripts. (J) KEGG analysis of differentially methylated transcripts.