Table 2 Comparison of clinical characteristics in HCC subtypes.

From: ALKBH5 acts a tumor-suppressive biomarker and is associated with immunotherapy response in hepatocellular carcinoma

Characteristics

Cluster1(N = 267)

Cluster2(N = 96)

P value

Gender (N = 363)

0.05

Female

79(29.6%)

39(40.6%)

 

Male

188(70.4%)

57(59.4%)

 

Age (N = 363)

0.42

<60

118(44.2%)

47(49.0%)

 

≥ 60

149(55.8%)

49(51.0%)

 

Neoplasm-Histologic-Grade (N = 358)

<0.001

G1/G2

183(69.6%)

47(49.5%)

 

G3/G4

80(30.4%)

48(50.5%)

 

TNM Stage (N = 360)

<0.001

Stage I/II

204(76.4%)

32(33.3%)

 

Stage III/IV

63(23.6%)

64(66.7%)

 

Vascular infiltration (N = 309)

0.07

Micro/Macro

72(30.5%)

32(43.8%)

 

None

164(69.5%)

41(71.2%)

 

Child-Pugh-Classification-Grade (N = 238)

0.35

A

168(89.8%)

48(94.1%)

 

B/C

19(10.2%)

3(5.9%)

 

AFP (N = 363)

0.01

≤ 400

169(80.9%)

44(65.7%)

 

>400

40(19.1%)

23(34.3%)

 

Adjacent-Hepatic-Tissue-Inflammation-Extent-Type (N = 232)

0.94

None

91(50.6%)

26(50.0%)

 

Mild/Severe

89(49.4%)

26(50.0%)

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