Table 2 Factors associated with 3-month all-cause mortality.

From: Determinants of outcomes in patients with hepatitis B virus-decompensated cirrhosis

 

Univariate model

Multivariate model

HR

(95%CI)

p value

HR

(95%CI)

p value

Age, year

1.031

1.012

1.050

0.001

1.037

1.014

1.061

0.001

Male sex

0.924

0.541

1.579

0.773

0.832

0.431

1.605

0.583

HBeAg-positivity

0.918

0.473

1.780

0.799

    

Ascites

3.311

1.914

5.729

 < 0.001

2.972

1.541

5.731

0.001

Hepatic encephalopathy

5.617

3.505

9.004

 < 0.001

3.307

1.767

6.188

 < 0.001

APF (ng/ml)

1.001

0.999

1.002

0.442

    

Platelet (103/μL)

1.006

1.002

1.010

0.004

0.999

0.994

1.005

0.810

ALT ≧ 5 × ULN

4.040

2.565

6.365

 < 0.001

2.094

1.088

4.030

0.027

Albumin (g/dL)

0.586

0.385

0.894

0.013

1.219

0.658

2.259

0.530

Total bilirubin (mg/dL)

1.096

1.071

1.122

 < 0.001

    

Prothrombin time (s)

1.070

1.053

1.088

 < 0.001

    

Creatinine (mg/dL)

1.102

0.989

1.227

0.077

    

MELD score

1.134

1.105

1.164

 < 0.001

1.101

1.058

1.146

 < 0.001

HBV DNA (Log10 IU/ml)

1.239

1.064

1.442

0.006

1.147

1.004

1.312

0.044

ETV

0.881

0.503

1.545

0.659

    
  1. Cox proportional hazards models. HBeAg, hepatitis B e antigen ; AFP, alpha-fetoprotein; ALT, alanine aminotransferase; ULN, upper limited normal; MELD, Model for End-Stage Liver Disease. ETV, entecavir.
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