Table 3 Antigen sensitivities and specificities. Table shows the IgG, IgM, and IgG + IgM sensitivities and specificities obtained using the vibrant microarray, and a comparison with the sensitivities and specificities of the current gold standard for respective pathogens.

Pathogen	IgM		IgG		IgM + IgG		Gold Std^{34,35,36,37,38,39,40,41,42,43,44,45,46,47,48}
	Sensitivity	Specificity	Sensitivity	Specificity	Sensitivity	Specificity	Sensitivity	Specificity
	(%)	(%)	(%)	(%)	(%)	(%)	(%)	(%)
Borrelia burgdorferi	60	100	94	100	100	100	Early:	95–100
							77.6
							Late:
							70–100
Babesia microti	79	98	91	97	99	96	70–80	94–100
Bartonella henselae	81	99	96	99	100	98	100	96.8
Anaplasma phagocytophilum	94	100	100	100	100	100	92	100
Ehrlichia chaffeensis	84	100	100	99	100	99	83	100
Rickettsia typhi	86	100	83	100	97	100	83–100 (IFA IgG) 53–100 (IFA IgM)	91–100 (IFA IgG) 91–99 (IFA IgM)
Rickettsia rickettsii	43	99	71	99	86	98	85–100 (IFA IgG) 83–85 (IFA IgM)	99–100 (IFA IgG) 100 (IFA IgM)
Powassan virus	100	100	100	100	100	100	89	65(IFA IgG), 100 (IgM IFA)
Tickborne encephalitis	78	99	92	99	93	98	83–94 (IgG) 94–100 (IgM)	100 (IgM) 59–89 (IgG)
West Nile virus	25	100	80	100	85	100	100	70.3
Coxsackie virus	56	100	100	100	100	100	94–97	100
Cytomegalovirus	100	100	100	100	100	100	89.2	95
Epstein Barr virus VCA	100	100	96	100	97	100	71 (VCA IgG), 95 (VCA IgM)	99
Epstein Barr virus EBNA1	95	100	96	100	97	100	99	99
Parvovirus B19	90	99	98	98	99	97	92.7	100
Toxoplasma gondii	100	99	100	100	100	99	94.2 (Both IgG and IgM)	100 (both IgG and IgM)
HSV-1	100	100	98	100	98	100	97–100	98
HSV-2	100	100	98	100	98	100	97–100	98
HHV-6	95	100	95	100	95	100	95	98.8

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