Fig. 5

(A) RMSF analysis of derivatives THD1, THD3, and THD5 on CYP51 complexes; 3D structure highlighting the significant fluctuations observed: Leu200-Ser226 (red), Arg248-Tyr258 (blue), and Arg400-His420 (yellow). (B) RMSF analysis of derivative THD5 on CYP2C9 complex.