Table 1 Baseline characteristics of case and matched control group.
Variables | Case group (n = 715,872) | Matched control group (n = 1,431,728) |
|---|---|---|
No. (%) | No. (%) | |
Age (years) | ||
Mean ± SD | 53.4 ± 15.4 | 53.4 ± 15.4 |
Age group (years) | ||
20–29 | 37,335 (5.2) | 74,670 (5.2) |
30–39 | 114,352 (16.0) | 228,704 (16.0) |
40–49 | 150,444 (21.0) | 300,888 (21.0) |
50–59 | 159,717 (22.3) | 319,434 (22.3) |
60–69 | 129,601 (18.1) | 259,202 (18.1) |
70–79 | 91,272 (12.7) | 182,544 (12.7) |
≥ 80 | 33,151 (4.6) | 66,286 (4.6) |
Sex | ||
Male | 332,705 (46.5) | 665,400 (46.5) |
Female | 383,167 (53.5) | 766,328 (53.5) |
Year of cholecystectomy | ||
2004 | 18,503 (2.6) | 37,006 (2.6) |
2005 | 22,209 (3.1) | 44,418 (3.1) |
2006 | 25,896 (3.6) | 51,792 (3.6) |
2007 | 27,778 (3.9) | 55,556 (3.9) |
2008 | 30,969 (4.3) | 61,938 (4.3) |
2009 | 34,446 (4.8) | 68,892 (4.8) |
2010 | 36,990 (5.2) | 73,980 (5.2) |
2011 | 40,825 (5.7) | 81,650 (5.7) |
2012 | 43,380 (6.1) | 86,760 (6.1) |
2013 | 44,572 (6.2) | 89,144 (6.2) |
2014 | 45,388 (6.3) | 90,776 (6.3) |
2015 | 47,033 (6.6) | 94,064 (6.6) |
2016 | 52,504 (7.3) | 105,008 (7.3) |
2017 | 55,851 (7.8) | 111,702 (7.8) |
2018 | 59,719 (8.3) | 119,434 (8.3) |
2019 | 64,841 (9.1) | 129,674 (9.1) |
2020 | 64,968 (9.1) | 129,934 (9.1) |
Charlson Comorbidity Index | ||
0 | 279,808 (39.1) | 864,019 (60.3) |
1 ≤ CCI < 3 | 343,010 (47.9) | 466,844 (32.6) |
3 ≤ CCI | 93,054 (13.0) | 100,865 (7.0) |
Death | 49,570 (6.9) | 103,186 (7.2) |
Person-years | ||
Total | 4,643,824 (0.0) | 9,261,693 (0.0) |
Person-years ≤ 5 | 320,647 (44.8) | 644,606 (45.0) |
5 ≤ Person-years < 10 | 222,799 (31.1) | 442,780 (30.9) |
Person-years ≥ 10 | 172,426 (24.1) | 344,342 (24.1) |
Cancer at all sites | 39,692 (5.5) | 71,709 (5.0) |
GI & HBP cancer | 15,736 (2.2) | 29,169 (2.0) |
Esophagus (C15) | 420 (2.7) | 960 (3.3) |
Stomach (C16) | 5,068 (32.2) | 10,265 (35.2) |
Small intestine (C17) | 97 (0.6) | 151 (0.5) |
Colorectum (C18–C20) | 4,374 (27.8) | 9,299 (31.9) |
Anus (C21) | 54 (0.3) | 126 (0.4) |
Liver (C22) | 3,413 (21.7) | 5,094 (17.5) |
Intrahepatic bile duct (C22.1) | 967 (6.1) | 1,082 (3.7) |
Hepatocellular carcinoma and others (C22 except 22.1) | 2,446 (15.5) | 4,012 (13.8) |
Extrahepatic bile duct (C24) | 1,045 (6.6) | 1,087 (3.7) |
Pancreas (C25) | 1,238 (7.9) | 2,133 (7.3) |
Unspecified digestive system (C26) | 27 (0.2) | 54 (0.2) |
