Table 3 Hazard ratio of gastrointestinal and hepato-biliary-pancreatic cancer in case group compared to the age and sex-matched control group adjusted for Charlson Comorbidity Index.

From: Increased diagnosis of hepato-biliary-pancreatic cancer after cholecystectomy: a population-based study

Cancer Type

Before adjusted

After adjusted

HR

95% C.I.

HR

95% C.I.

Esophagus (C15)

0.872

0.778

0.978

0.762

0.677

0.857

Stomach (C16)

0.985

0.952

1.018

0.879

0.849

0.910

Small intestine (C17)

1.275

0.988

1.646

1.064

0.818

1.384

Colorectum (C18–C20)

0.937

0.904

0.971

0.826

0.796

0.857

Anus (C21)

0.852

0.620

1.172

0.714

0.514

0.990

Liver (C22)

1.334

1.277

1.393

1.023

0.978

1.070

Intrahepatic bile duct (C22.1)

1.779

1.631

1.940

1.450

1.325

1.585

Hepatocellular carcinoma and others (C22 except 22.1)

1.213

1.154

1.276

0.914

0.868

0.962

Extrahepatic bile duct (C24)

1.913

1.758

2.083

1.585

1.452

1.730

Pancreas (C25)

1.157

1.079

1.241

0.939

0.874

1.009

Unspecified digestive system (C26)

0.996

0.627

1.581

0.788

0.490

1.266

All GI and HBP cancers

1.075

1.054

1.096

0.917

0.899

0.936

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