Table 3 Association of chronic HBV infection with anemia in pregnancy in the validation retrospective cohort.

From: Positive association between chronic hepatitis B virus infection and anemia in pregnancy in Southern China

 

Healthy controls (n = 129)

HBV case (n = 86)

OR (95% CI)

p values

Age in years, (mean ± SD)

30.2 ± 3.7

30.9 ± 4.0

 

n.s.

ALT (U/L)*, median (min., max.)

12 (5, 97)

21 (6, 325)

 

< 0.0001

AST (U/L)*, median (min., max.)

16 (10, 49)

21 (13, 277)

 

< 0.0001

Anemia in the first trimester, n (%)

6 (4.7%)

11 (12.8%)

3.01 (1.07–8.47)

0.0303

Anemia in the second trimester, n (%)

54 (41.9%)

43 (50%)

1.39 (0.80–2.40)

n.s.

Anemia in the third trimester, n (%)

53 (41.1%)

52 (60.5%)

2.19 (1.25–3.83)

0.0054

Anemia in any trimester, n (%)

67 (51.9%)

60 (69.8%)

2.13 (1.20–3.79)

0.0092

  1. ALT alanine transaminase, AST aspartate aminotransferase, HBV hepatitis B virus, OR odd ratio.*Data derived from 118 controls and 83 HBV cases.
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