Table 3 Histomorphometric pulpal reactions in experimental groups.

	Hard-tissue bridge		Barrier continuity				Inflammation intensity				Infiltration depth				Calcification		Necrosis		Bleeding & hyperemia		Barrier thickness (µm)
	0*	1**	0*	1**	2***	3****	0^η	1 ^ηη	2 ^ηηη	3 ^ηηηη	0^€	1^€€	2^€€€	3^€€€€	0^£	1^££	0^¥	1^¥¥	0^§	1^§§
MTA	5 (29.4%)	12 (70.6%)	5 (29.4%)	2 (11.8%)	3 (17.6%)	7 (41.2%)	10(58.8)	5 (29.4%)	2 (11.8)	0 (0.0%)	10 (58.8%)	5 (29.4%)	1 (5.9%)	1 (5.9%)	8 (47.1%)	9 (52.9%)	17 (100.0%)	0 (0.0%)	7 (41.2%)	10 (58.8%)	57.41 ± 49.731
MTA + ZnO	13 (76.5%)	4 (23.5%)	13 (76.5%)	2 (11.8%)	2 (11.8%)	0 (0.0%)	13 (76.5%)	2 (11.8%)	1 (5.9%)	1 (5.9%)	13 (76.5%)	0 (0.0%)	4 (23.5%)	0 (0%)	11 (64.7%)	6 (35.3%)	15 (88.2%)	2 (11.8%)	8 (47.1%)	9 (52.9%)	6.59 ± 13.158
Total	18 (52.9%)	16 (47.1%)	18 (52.9%)	4 (11.8%)	5 (14.7%)	7 (20.6%)	23 (67.6%)	7 (20.6%)	3 (8.8%)	1 (2.9%)	23 (67.6%)	5 (14.7%)	5 (14.7%)	1 (2.9%)	19 (55.9%)	15 (4.1%)	32 (94.1%)	2 (5.9%)	15 (44.1%)	19 (55.9%)

* Lack of bridge formation. **Primitive formation of bridge; extending to less than half of the exposure site. ***Partial formation of bridge; encompassing more than half of the exposure site but leaving the exposure site patent. ****Complete formation of bridge.
^ηAbsent or very few inflammatory cells. ^ηηMild (an average of < 30 inflammatory cells). ^ηηηModerate (an average of 30—60 inflammatory cells). ^ηηηηSevere (an average > 60 inflammatory cells). ^€ No inflammatory cells observed. ^{€ €} Inflammatory cell infiltration limited to coronal third of the pulp. ^{€ € €} Inflammatory cell infiltration extended to middle third of the pulp. ^{€ € € €} Inflammatory cell infiltration extended to apical third of the pulp. ^£Absence of diffuse pulpal calcification. ^££Presence of diffuse pulpal calcification. ^¥Absence of denatured or autolyzed proteins within the pulpal tissue (as a hallmark of tissue vitality). ^¥¥Presence of denatured or autolyzed proteins within the pulpal tissue (as a hallmark of tissue necrosis). ^§Absence of extravasated erythrocytes from pulpal blood vessels. ^§§Presence of extravasated erythrocytes from pulpal blood vessels.

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