Table 1 Characteristics of patients in the study.

From: Characterization of gut dysbiosis and intestinal barrier dysfunction in patients with metabolic dysfunction-associated steatotic liver disease and chronic kidney disease: a comparative study

Characteristics

MASLD (n = 90)

CKD (n = 60)

Both diseases (n = 30)

p-value

Age (years)

64.1 ± 7.8

66.0 ± 11.5

67.3 ± 11.9

0.232

Gender

 Male

46 (51.1)

32 (53.3)

15 (50.0)

0.946

 Female

44 (48.9)

28 (46.7)

15 (50.0)

Body mass index (kg/m2)

27.4 ± 3.6

24.2 ± 4.3

27.6 ± 4.1

< 0.001*

Presence of type 2 diabetes

34 (37.8)

22 (36.7)

14 (46.7)

0.627

Presence of hypertension

53 (58.9)

39 (65.0)

16 (53.3)

0.541

Presence of dyslipidemia

40 (44.4)

21 (35.0)

15 (50.0)

0.331

Serum creatinine (mg/dL)

0.9 ± 1.2

2.4 ± 1.4

1.8 ± 0.8

< 0.001*

eGFR (mL/min/1.73 m2)

86.8 ± 14.8

38.3 ± 12.6

46.8 ± 9.7

< 0.001*

Hemoglobin (g/dL)

14.0 ± 1.2

11.5 ± 1.7

12.5 ± 2.0

< 0.001*

Platelet count (103/µL)

232.3 ± 58.1

231.3 ± 76.7

239.7 ± 65.9

0.845

Aspartate aminotransferase (IU/L)

28.1 ± 13.3

20.9 ± 10.0

25.0 ± 18.8

0.006*

Alanine aminotransferase (IU/L)

32.8 ± 18.8

22.5 ± 28.6

21.8 ± 10.4

0.007*

Albumin (g/dL)

4.2 ± 0.9

4.1 ± 0.4

4.3 ± 0.3

0.636

Uric acid (mg/dL)

6.2 ± 1.4

7.7 ± 2.1

7.2 ± 1.7

< 0.001*

Urine albumin creatinine ratio (mg/g)

27.7 ± 13.4

179.5 ± 307.6

163.0 ± 144.4

0.239

Liver stiffness measurement (kPa)

9.7 ± 6.6

6.2 ± 4.4

8.7 ± 6.6

0.003*

Controlled attenuation parameter (dB/m)

315.3 ± 37.4

200.5 ± 36.3

296.7 ± 38.0

< 0.001*

  1. Data as shown in mean ± SD; n (%); * p < 0.05 using one-way ANOVA; eGFR estimated glomerular filtration rate.