Table 3 Adjusted hazard ratios for overall survival by RCC subtypes in the entire cohort; metastasis-naive and metastatic patients (adjusted for TNM stage).
Entire cohort (n = 604) | ||||
|---|---|---|---|---|
OS | ||||
HR | 95% CI | p-value | ||
Pathologic subtypes | Clear cell RCC (n = 504) | Reference | ||
Papillary RCC (n = 44) | 1.023 | 0.639–1.636 | 0.925 | |
Chromophobe RCC (n = 17) | 1.411 | 0.720–2.766 | 0.315 | |
Rare RCC (n = 39) | 2.196 | 1.418–3.402 | < 0.001 | |
Pathologic T stage | pT3a (n = 359) | Reference | ||
pT3b (n = 172) | 1.224 | 0.931–1.610 | 0.147 | |
pT3c (n = 28) | 1.580 | 0.824–3.028 | 0.168 | |
pT4 (n = 45) | 1.949 | 1.286–2.953 | 0.002 | |
Pathologic N stage | pN0 (n = 163) | Reference | ||
pN1 (n = 92) | 1.398 | 0.952–2.053 | 0.087 | |
pNx (n = 349) | 0.850 | 0.633–1.142 | 0.282 | |
Pathologic M stage | pM0 (n = 447) | Reference | ||
pM1 (n = 101) | 2.560 | 1.853–3.538 | < 0.001 | |
pMx (n = 56) | 2.249 | 1.547–3.269 | < 0.001 | |