Table 3 Effects of PGEO-NE on carrageenan-induced paw edema.

From: The anti-nociceptive and anti-inflammatory effects of Pelargonium graveolens essential oil nanoemulsion in mice

 

Paw edema thickness (Δ) in mm (Mean ± SEM)

Treatment

1 h

2 h

3 h

4 h

5 h

Vehicle

0.12 ± 0.01

0.103 ± 0.004

0.098 ± 0.005

0.091 ± 0.006

0.095 ± 0.004

DEX (5 mg/kg)

0.06 ± 0.005***

0.046 ± 0.009***

0.033 ± 0.01**

0.033 ± 0.01**

0.034 ± 0.011**

DIC (10 mg/kg)

0.064 ± 0.006***

0.066 ± 0.007**

0.065 ± 0.005**

0.058 ± 0.0054

0.0516 ± 0.002**

PGEO 10 (mg/kg)

0.096 ± 0.0085

0.095 ± 0.005

0.105 ± 0.014

0.098 ± 0.016

0.08 ± 0.0086

PGEO-NE 50 (mg/kg)

0.053 ± 0.007***

0.063 ± 0.008***

0.047 ± 0.008*

0.03 ± 0.009**

0.014 ± 0.008***

PGEO-NE 100 (mg/kg)

0.056 ± 0.005***

0.058 ± 0.005***

0.038 ± 0.011**

0.02 ± 0.008***

0.005 ± 0.003***

  1. Data represents the difference in paw thickness at the beginning of the procedure, * P < 0.05, ** P < 0.01 and *** P < 0.001 versus vehicle.
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