Table 1 Univariate and multivariate regression analyses in NSCLC patients.
From: The potential of secretogranin V as a prognostic biomarker in non-small cell lung cancer
Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
Pathologic T stage | 1023 | < 0.001 | |||
T1 | 290 | Reference | Reference | ||
T2 | 574 | 1.399 (1.092–1.793) | 0.008 | 1.242 (0.877–1.757) | 0.222 |
T3 | 117 | 2.270 (1.622–3.177) | < 0.001 | 2.003 (1.246–3.220) | 0.004 |
T4 | 42 | 2.764 (1.769–4.318) | < 0.001 | 1.859 (0.958–3.607) | 0.067 |
SCG5 | 1026 | 0.032 | |||
Low | 510 | Reference | Reference | ||
High | 516 | 1.241 (1.018–1.511) | 0.032 | 1.047 (0.790–1.387) | 0.750 |
Pathologic M stage | 796 | 0.001 | |||
M0 | 764 | Reference | Reference | ||
M1 | 32 | 2.287 (1.451–3.605) | < 0.001 | 2.150 (1.216–3.800) | 0.008 |
Primary therapy outcome | 799 | < 0.001 | |||
Gender | 1026 | 0.117 | |||
Female | 413 | Reference | |||
Male | 613 | 1.176 (0.959–1.443) | 0.119 | ||
Age | 1010 | 0.022 | |||
≤ 65 | 447 | Reference | Reference | ||
> 65 | 563 | 1.264 (1.033–1.547) | 0.023 | 1.126 (0.856–1.479) | 0.396 |
Location | 419 | 0.553 | |||
Central lung | 207 | Reference | |||
Peripheral lung | 212 | 1.095 (0.812–1.477) | 0.553 | ||
Neoplasm type | 1026 | 0.230 | |||
Adenocarcinoma | 530 | Reference | |||
Squamous cell carcinoma | 496 | 1.129 (0.926–1.375) | 0.230 | ||
Number pack years smoked | 784 | 0.446 | |||
< 40 | 316 | Reference | |||
≥ 40 | 468 | 1.094 (0.867–1.381) | 0.447 | ||
