Table 1 Baseline characteristics of patients with and without liver steatosis.

From: Association of cardiometabolic markers with hepatic steatosis and liver fibrosis in population without obesity and diabetes

Characteristic

Level

Overall (n = 1489)

Control (n = 917)

Liver steatosis (n = 572)

P

Age (Years)

 

45.74 ± 0.83

41.82 ± 1.07

51.83 ± 1.07

< 0.001

20 ~ 39 years

551(41.07)

417(51.68)

134(24.58)

< 0.001

40 ~ 59 years

506(34.61)

289(29.51)

217(42.55)

 

60 ~ 80 years

432(24.32)

211(18.81)

221(32.87)

 

Gender

Female

739(49.39)

484(53.73)

255(42.65)

0.009

Male

750(50.61)

433(46.27)

317(57.35)

 

Race

Non-Hispanic white

548(66.21)

315(64.04)

233(69.59)

0.001

Non-Hispanic black

299(8.66)

228(11.07)

71(4.93)

 

Mexican American

174(8.05)

97(7.86)

77(8.36)

 

Other Hispanic

144(6.36)

83(6.40)

61(6.29)

 

Other race

324(10.72)

194(10.63)

130(10.83)

 

Education

Less than high school

238(9.02)

138(8.66)

100(9.59)

0.757

High school graduate

342(23.87)

209(23.28)

133(24.78)

 

Some college

443(28.60)

287(29.48)

156(27.22)

 

College graduate or above

466(38.51)

283(38.58)

183(38.41)

 

Marital status

No

594(39.06)

412(46.11)

182(28.10)

< 0.001

Yes

895(60.94)

505(53.89)

390(71.90)

 

Smoke

Former

316(25.49)

169(20.81)

147(32.76)

0.021

Never

902(58.56)

565(63.28)

337(51.23)

 

Now

271(15.95)

183(15.91)

88(16.01)

 

Alcohol

No

142(6.32)

89(6.80)

53(5.57)

0.285

Yes

1347(93.68)

828(93.20)

519(94.43)

 

Activity

Moderate

350(25.57)

203(23.27)

147(29.16)

0.046

No

659(36.38)

391(34.71)

268(38.99)

 

Vigorous

480(38.05)

323(42.02)

157(31.85)

 

BMI (kg/m2)

 

24.88 ± 0.14

24.08 ± 0.16

26.13 ± 0.17

< 0.001

Waistline(cm)

 

89.15 ± 0.37

85.93 ± 0.50

94.16 ± 0.49

< 0.001

Height(cm)

 

168.63 ± 0.35

168.04 ± 0.53

169.55 ± 0.52

0.072

FBG(mmol/L)

 

5.53 ± 0.02

5.44 ± 0.03

5.68 ± 0.02

< 0.001

Insulin(uU/mL)

 

7.79 ± 0.20

7.03 ± 0.27

8.98 ± 0.28

< 0.001

HbA1c (%)

 

5.34 ± 0.02

5.30 ± 0.01

5.41 ± 0.03

< 0.001

ALT (U/L)

 

19.61 ± 0.38

17.96 ± 0.47

22.16 ± 0.74

< 0.001

AST(U/L)

 

20.95 ± 0.30

20.28 ± 0.38

22.00 ± 0.52

0.016

GGT (IU/L)

 

24.40 ± 0.78

20.18 ± 0.70

30.94 ± 1.96

< 0.001

Cr (umol/L)

 

76.41 ± 0.50

75.90 ± 0.74

77.20 ± 1.01

0.369

UA (umol/L)

 

305.16 ± 3.51

293.11 ± 4.31

323.86 ± 5.52

< 0.001

BUN (mg/mL)

 

14.30 ± 0.17

14.02 ± 0.21

14.73 ± 0.30

0.059

TG (mg/mL)

 

92.69 ± 1.82

77.90 ± 1.60

115.68 ± 4.24

< 0.001

TC (mg/mL)

 

187.61 ± 1.72

181.58 ± 2.05

196.99 ± 3.81

0.003

HDL (mg/mL)

 

58.74 ± 0.80

59.94 ± 0.79

56.86 ± 1.21

0.021

hsCRP (mg/L)

 

2.64 ± 0.23

2.46 ± 0.34

2.91 ± 0.52

0.548

HOMA-IR

 

1.95 ± 0.06

1.73 ± 0.07

2.30 ± 0.08

< 0.001

LSM (kPa)

 

4.95 ± 0.07

4.80 ± 0.10

5.19 ± 0.14

0.045

CAP (dB/m)

 

236.65 ± 1.63

204.98 ± 1.78

285.88 ± 1.97

< 0.001

CMI

 

0.44 ± 0.01

0.34 ± 0.01

0.59 ± 0.03

< 0.001

AIP

 

−0.22 ± 0.01

−0.29 ± 0.01

−0.11 ± 0.01

< 0.001

TyG

 

8.26 ± 0.02

8.11 ± 0.02

8.50 ± 0.02

< 0.001

eGDR

 

9.29 ± 0.09

9.82 ± 0.11

8.47 ± 0.10

< 0.001

Hypertension

No

1016(73.63)

677(79.84)

339(63.98)

< 0.001

Yes

473(26.37)

240(20.16)

233(36.02)

 

ASCVD

No

1380(93.68)

860(95.56)

520(90.75)

0.021

Yes

109(6.32)

57(4.44)

52(9.25)

 

CKD

No

1323(92.04)

825(92.94)

498(90.63)

0.068

Yes

166(7.96)

92(7.06)

74(9.37)

 

Cancer

No

1350(89.28)

845(89.38)

505(89.11)

0.92

Yes

139(10.72)

72(10.62)

67(10.89)

 
  1. BMI: Body mass index; FBG: Fasting blood glucose; HbA1c: Hemoglobin A1c; ALT: Alanine transaminase; AST: Aspartate transaminase; GGT: Gamma-glutamyl transferase; Cr: Creatinine; UA: Uric acid; BUN: Blood urea nitrogen; TG: Triglycerides; TC: Total cholesterol; HDL: High-density lipoprotein; hsCRP: High-sensitivity C-reactive protein; HOMA-IR: Homeostasis model assessment of insulin resistance; LSM: Liver stiffness measurement; CAP: Controlled attenuation parameter; CMI: Cardiac metabolic index; AIP: Atherogenic index of plasma; TyG: Triglyceride glucose index; eGDR: Estimated glucose disposal rate; ASCVD: Atherosclerotic cardiovascular disease; CKD: Chronic kidney disease.