Fig. 3

Signal detection of GLP-1 RA-related NAEs. (A) Heatmap visualization of RORs for 60 NEAs meeting case threshold (≥ 3 reports). NAEs labelled in dark red are GLP-1 RA-related NAEs. (B) Case frequency distribution of 19 GLP-1 RA-related NAEs. (C) Methodological concordance analysis using Venn diagram. Abbreviations: ROR, reporting odds ratio; PRR, proportional reporting ratio; EBGM, empirical Bayesian geometric mean; BCPNN, Bayesian confidence propagation neural network; NAEs, neurological adverse events; GLP-1 RAs, glucagon-like peptide-1 receptor agonists.