Table 4 Multivariable Cox regression analysis for the secondary outcome of heart failure.

From: Klotho plasma levels are an independent predictor of mortality in women with acute coronary syndrome

Gender

Variable

HR (CI 95%)

p

Female

MRAs

9.22 (3.21–26.55)

< 0.001

FGF23

1.03 (1.01–1.06)

0.009

Insulin

5.56 (1.71–18.31)

0.008

ASA

0.23 (0.06–0.94)

0.042

Male

FGF 23

1.04 (1.03–1.06)

< 0.001

PTH

1.14 (1.06–1.23)

0.002

Age

1.06 (1.02–1.09)

0.001

Oral antidiabetic drugs

3.02 (1.60–5.71)

0.001

LVEF < 40%

3.73 (1.99–6.95)

< 0.001

Diltiazem

4.97 (1.68–14.69)

0.005

Hypertension

2.23 (1.03–4.84)

0.043

  1. ASA: acetylsalicylic acid; eGFR: estimated glomerular filtration rate; FGF23: fibroblast growth factor 23; LVEF: left ventricular ejection fraction; MRAs: mineralocorticoid receptor antagonists; HR: Hazar Ratio; PTH: parathormone.