Fig. 5

Significant metabolite and lipoprotein alterations in eight-group comparison (non-PD Control, PD genetic phenotype with GBA groups excluded, PD sporadic, PD GBA groups divided by severity grade). Heatmap of p-value FDR-significant findings checked via ANOVA statistical testing. Dot plot of methionine shows lowest level of this metabolite, shown as means and SEMs, in GBA groups.