Fig. 1
From: The adverse effects of chemotherapy on bone mass are not prevented by senolytics
D + Q failed to prevent early bone loss caused by AC. (a) Schematic of experimental design created with BioRender.com. (b) Percent change calculated from measurements taken the day before the beginning of treatment and before sacrifice. (c) μCT analysis of trabecular bone volume over tissue volume (BV/TV) and (d) trabecular microarchitecture in fifth lumbar (L5) vertebrae after sacrifice (n = 9/group). (e) Quantitative RT-PCR analysis of mRNA from the sixth lumbar (L6) vertebrae. Bars represent mean ± SD; p-values by 2-way ANOVA with Tukey’s multiple comparisons test. The most relevant comparisons between individual groups are displayed.
