Fig. 3
From: The adverse effects of chemotherapy on bone mass are not prevented by senolytics
D + Q did not alter the loss of bone mass caused by TAC. (a) Schematic of experimental design created with BioRender.com. Quantitative μCT analysis of (b) cortical thickness at the midshaft (diaphysis) or the distal end (metaphysis) of the femur; and (c) trabecular bone volume over tissue volume (BV/TV) and (d) microarchitecture in fifth lumbar vertebrae. (e) Quantitative RT-PCR analysis of mRNA from the sixth lumbar vertebrae. Bars represent mean ± SD; p-values by 2-way ANOVA with Tukey’s multiple comparisons test. The most relevant comparisons between individual groups are displayed.
