Fig. 8 | Scientific Reports

Fig. 8

From: The adverse effects of chemotherapy on bone mass are not prevented by senolytics

Fig. 8

Cellular senescence was not detected up 12 months after cessation of TAC. Quantitative RT-PCR of senescence marker genes in (a) sixth lumbar (L6) vertebrae, (b) femur and tibia cortical bone, (c) kidney, and (d) liver from mice described in Fig. 7a (n = 5/group). Bar graphs represent mean ± SD; p-values by unpaired two-tailed Student’s t-test; with Welch’s correction for Il-6 (d) and Mann–Whitney test for Cdkn2a (b,c), Hmgb1 (c), and Mmp13 (d).

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