Fig. 4
From: The glymphatic system was impaired in spontaneously hypertensive rats
Region-of-interest (ROI)-based analysis. Average signal intensity changes over time refecting Gd-DTPA contrast agent distribution in the aqueduct (A, P = 0.0079), cerebellum (B, P = 0.5283), cortex (C, P = 0.5211), hippocampus (D, P = 0.0076), medulla (E, P = 0.4910), olfactory bulb (F, P = 0.0718), and pons (G, P = 0.1594). *signifcant diference in the area under the curve (AUC) across the two groups indicates a diferential distribution of contrast agent. Independent-samples T Test was used for comparison between the two groups, and P < 0.05 was considered statistically significant.Levels of significance are defined as *p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001; ****p ≤ 0.0001, n = 10.
A.
