Table 3 Characteristics of patients according to the evolution of iron status under ETI.

Age

(years, median [Q1;Q3])

32.7 [25.5; 39.2]

29.1 [22.6; 33.2]

28.4 [21; 31.9]

30.9 [23.1; 35.1]

0.03

Female sex (%)

20%

44%

23.5%

66%

< 0.001

BMI at V0

(kg.m^− 2, median [Q1;Q3])

21.2 [19.7; 23.7]

20.0 [18.4; 22.2]

20.5 [18.7; 21]

21.4 [18.8; 23.2]

0.003

BMI variations at V12 (%)

4.9 ± 7.3

7.2 ± 9

6.9 ± 9.8

6.6 ± 9.6

0.02

CFRD at V0 (n, %)

13%

22%

41%

34%

0.01

PPI use (n, %)

36%

34%

47%

48%

ns

Pseudomonas aeruginosa positivity at V0 (%)

56%

73%

76%

60%

ns

Absence of Pseudomonas aeruginosa at V12 in patients with positive sputum at V0 (%)

29%

40%

16%

16%

ns

Haemoglobin at V0

(g/dL, median [Q1;Q3])

15.9 [14.3; 15.8]

14.1 [13.2; 14.9]

14.9 [14.4; 16]

13.1 [12.2; 14.2]

< 0.001

Haemoglobin variations at V12 (%)

-0.01 ± 12.2

4.9 ± 9.3

-0.8 ± 6.3

2.3 ± 14.3

0.02

CRP at V0 (mg/L)

2.4 [1.2; 6]

9.7 [4.1; 21.2]

2.7 [1.5; 6.2]

7.6 [2.9; 19.9]

< 0.001

CRP variations at V12 (%)

− 72 [− 88; − 31]

− 88 [− 96; − 77]

− 50 [− 74; − 94]

− 78 [− 90; 0]

< 0.001

Globulin at V0 (g/L)

11 [9.8; 13.5]

13.5 [11.8; 15.9]

12.8 [10.6; 13.9]

13 [11.9; 16.3]

< 0.001

Globulin variations at V12 (%)

− 12 [-17.5; -2.4]

-15.2 [-24; -7.2]

-19.8 [-25.2; -1.5]

-17.1 [-27.5; -5.7]

ns

Vitamin D at V0

62 [42; 78]

61 [39; 75]

59 [47; 73]

52 [35; 74]

ns

Vitamin D variations at V12 (%)

16 [-7; 60]

18 [-10; 56]

25 [2.6 : 58]

15.8 [-6; 48]

ns

FEV1 variations at V12 (%)

17.4 [9.7; 30.1]

37.1 [17.2; 52.8]

23.6 [6.2; 45]

26.1 [15.4; 45]

< 0.001