Table 2 Comparison of mean SUVmax values in selected organs and tumor-to-liver SUVmean ratios at 60-min post-injection of [68Ga]Ga-CCZ01048 and [18F]FDG.
From: First-in-human dosimetry and safety evaluation of 68Ga-αMSH derivative for PET imaging of melanoma
Organ | SUVmax | Tumor SUVmax /liver SUVmean Ratio | ||
|---|---|---|---|---|
[18F]FDG | [68Ga]Ga-CCZ01048 | [18F]FDG | [68Ga]Ga-CCZ01048 | |
Liver | 7.5 ± 1.1 | 1.57 ± 0.28 | 2.8 | 7.3 |
Lung | 2.3 ± 0.29 | 0.88 ± 0.15 | 3.2 | 5.8 |
Brain | 6.5 ± 0.73 | 0.05 ± 0.02 | 2.5 | 4.1 |
Muscle | 2.9 ± 0.21 | 0.64 ± 0.16 | 3.1 | 8.5 |
Kidney | 11.2 ± 1.3 | 5.19 ± 0.85 | – | – |
Mean ± SD | 6.1 ± 3.6 | 1.7 ± 2.0 | 2.9 ± 0.3 | 6.4 ± 1.9 |
