Fig. 6 | Scientific Reports

Fig. 6

From: Neutrophil extracellular traps aggravate uremic cardiomyopathy by inducing myocardial fibroblast pyroptosis

Fig. 6

NET treatment induced fibrosis and pyroptosis in cardiac fibroblasts (A) The expression of collagen1 and α-SMA was detected by Western blot. (B) Pyroptosis was observed under a transmission electron microscope. Red arrowheads indicate the vesicles released from the plasma membrane. Scale bar: 2 μm. (C) The expression of NLRP3, GSDMD-N, and caspase-1 was detected by Western blot. α-SMA, α-smooth muscle actin; NLRP3, NOD-like receptor protein 3; GSDMD, gasdermin D; GAPDH, glyceraldehyde-3-phosphate dehydrogenase, **P < 0.01.

Back to article page