Fig. 4
From: 5-Hydroxymethylcytosine signatures as diagnostic biomarkers for septic cardiomyopathy
5hmC markers’ diagnosis for SCM in the study cohort. (A) Principle component analysis (PCA) plot of 5hmC markers in evDNAs from SCM and sepsis samples. (B) Heatmaps of 6 5hmC markers with treatment response, batch and sex information labeled in the study cohorts. Unsupervised hierarchical clustering was performed across genes and samples. (C) ROC curves showing the results of the prediction model based on 5hmC markers differentiating patients with SCM from sepsis. (D) Confusion matrix showing model prediction ability for validation cohort. (E) ROC curves showing the results of the prediction model based on 5hmC markers differentiating patients with SCM from sepsis. (F) Confusion matrix showing model prediction ability for validation cohort.
