Fig. 3

Overlap and classification of vitamin D target genes between VitDPAS and VitDHiD studies. (A) A Venn diagram highlights the intersection of 758 significant (p < 0.05) in vivo vitamin D target genes identified in the VitDPAS study and 1,654 target genes from the VitDHiD study. (B) The quality of transcriptome datasets for the 232 shared target genes at d0 and d1 was assessed using dimensionality reduction, depicted in a MDS plot. (C) Based on the expression profiles of the 232 common target genes, the 70 participants across both studies were categorized into high (green), mid (yellow), and low (red) vitamin D responders.