Fig. 6

Correlation heat map between the cytokine plasma levels, laboratory parameters and the top 23 most abundant genera in gut microbiota of term newborns with critical congenital heart defects with or without necrotizing enterocolitis (NEC) across the perioperative period. Color scale bars show a range of nonparametric Spearman correlation (r). The red color corresponds to a strong positive correlation, the purple color - a strong negative correlation. Only significant correlations are presented (p < 0.03). No-NEC_BS and No-NEC_AS represent no-NEC newborns before and after cardiac surgery, NEC_BS and NEC_AS represent NEC newborns before and after cardiac surgery, respectively.