Table 3 KSPD scores after adjusting for possible covariates in smoking status during pregnancy: ANCOVA results.

From: Direct and indirect effects of smoking during pregnancy on child development: The Japan Environment and Children’s Study

  

Male

Female

Q1: non-smokers

Q2: ex-smokers who quit before pregnancy

Q3: ex-smokers who quit during pregnancy

Q4: current smokers

p value*

Q1: non-smokers

Q2: ex-smokers who quit before pregnancy

Q3: ex-smokers who quit during pregnancy

Q4: current smokers

p value*

  

Estimate ± 95%Cl

2y

P-M

91.9 (90.9–92.8)

91.8 (90.3–93.4)

94.3 (91.9–96.6)

94.3 (89.9–98.6)

0.234

93.2 (92.2–94.2)

94.1 (92.6–95.6)

95.1 (92.6–97.5)

100.9 (96.7–105.1)

0.004

C-A

93.0 (92.4–93.7)

92.7 (91.7–93.8)

93.3 (91.7–94.9)

89.7 (86.8–92.6)

0.170

97.2 (96.5–97.9)

97.6 (96.4–98.7)

97.4 (95.6–99.2)

96.7 (93.6–99.7)

0.925

L-S

88.9 (88.1–89.7)

88.9 (87.6–90.2)

87.3 (85.4–89.3)

83.4 (79.8–87.0)

0.019

95.3 (94.5–96.1)

94.4 (93.2–95.7)

94.6 (92.7–96.6)

93.8 (90.4–97.3)

0.559

DQ

91.6 (91.0–92.1)

91.4 (90.5–92.3)

91.6 (90.2–92.9)

88.6 (86.1–91.0)

0.144

95.8 (95.3–96.4)

95.7 (94.8–96.6)

96.0 (94.6–97.5)

95.8 (93.3–98.3)

0.977

4y

P-M

87.6 (86.9–88.3)

87.7 (86.5–88.8)

87.9 (86.1–89.6)

86.8 (83.7–90.0)

0.954

89.6 (89.0–90.2)

89.5 (88.5–90.4)

88.7 (87.1–90.3)

92.0 (89.3–94.8)

0.232

C-A

93.7 (92.9–94.6)

93.7 (92.2–95.1)

90.3 (88.1–92.6)

86.9 (82.9–90.9)

 < 0.001

96.8 (96.0–97.6)

96.7 (95.5–98.0)

94.7 (92.7–96.7)

95.5 (92.1–98.9)

0.262

L-S

93.5 (92.6–94.5)

92.7 (91.2–94.3)

90.1 (87.7–92.5)

89.2 (84.9–93.6)

0.029

96.7 (95.9–97.6)

95.5 (94.2–96.8)

93.8 (91.7–96.0)

95.6 (91.9–99.2)

0.072

DQ

93.4 (92.6–94.2)

93.0 (91.7–94.4)

90.2 (88.1–92.3)

88.0 (84.2–91.8)

0.004

96.6 (95.9–97.3)

96.0 (94.9–97.1)

94.2 (92.3–96.0)

95.6 (92.5–98.8)

0.123

  1. P-M posture-motor, C-A cognitive-adaptive, L-S language-social, DQ developmental quotient, CI confidence interval.
  2. *ANCOVA with covariates of Pre-pregnancy BMI, maternal age at parturition, Annual household income, Parity, Birth weight, Maternal blood Cadmium concentration.