Table 3 The comparation of ovarian reserve and IVF/ICSI outcomes before and after PRP injection in subgroups.
The frequency of ovarian autologous PRP injection | One-treatment group | Two-treatment group | ||||
|---|---|---|---|---|---|---|
Before PRP injection | After PRP injection | P-value | Before PRP injection | After PRP injection | P-value | |
Number of cycles | 41 | 41 | 30 | 30 | ||
AMH (ng/ml) | 0.37 ± 0.28 | 0.42 ± 0.25 | 0.215 | 0.27 ± 0.18 | 0.44 ± 0.34 | 0.006 |
Antral follicle count | 2.66 ± 1.06 | 3.83 ± 1.96 | 0.002 | 2.57 ± 1.14 | 3.77 ± 1.96 | 0.005 |
Basal FSH (IU/L) | 12.43 ± 9.46 | 10.23 ± 6.14 | 0.029 | 11.02 ± 5.46 | 10.80 ± 5.21 | 0.862 |
Basal LH (IU/L) | 5.62 ± 5.50 | 4.55 ± 2.96 | 0.094 | 5.38 ± 2.35 | 5.17 ± 2.91 | 0.682 |
Basal oestradiol (pg/ml) | 52.90 ± 39.76 | 58.31 ± 47.08 | 0.345 | 43.05 ± 22.00 | 40.71 ± 19.47 | 0.644 |
Protocol | 0.068 | 0.028 | ||||
Progestin-primed ovarian stimulation | 21 | 14 | 12 | 6 | ||
Antagonist protocol | 18 | 27 | 15 | 24 | ||
Microstimulation | 2 | 0 | 3 | 0 | ||
Total length of stimulation (days) | 9.32 ± 3.62 | 8.83 ± 2.06 | 0.455 | 8.30 ± 1.91 | 9.07 ± 2.24 | 0.115 |
Total dosage of gonadotrophin (IU) | 2546.95 ± 1551.74 | 2421.34 ± 991.50 | 0.63 | 2120.00 ± 1117.12 | 2771.67 ± 869.57 | 0.009 |
Trigger day | ||||||
Peak oestradiol (pg/ml) | 752.46 ± 571.63 | 926.70 ± 688.83 | 0.046 | 657.64 ± 371.47 | 1109.93 ± 707.85 | 0.002 |
Number of follicles ≥ 14 mm | 2.59 ± 1.47 | 3.56 ± 2.05 | 0.014 | 2.43 ± 1.52 | 3.43 ± 1.36 | 0.009 |
Number of oocytes retrieved | 2.41 ± 1.95 | 3.68 ± 2.18 | 0.006 | 2.20 ± 1.61 | 3.47 ± 1.76 | 0.001 |
Procedure | 0.102 | 1 | ||||
IVF | 31 | 23 | 22 | 22 | ||
ICSI | 10 | 18 | 8 | 8 | ||
Number of normal fertilized zygotes | 1.44 ± 1.61 | 1.90 ± 1.53 | 0.174 | 1.27 ± 1.20 | 2.20 ± 1.67 | 0.008 |
Number of usable cleavage embryos | 1.02 ± 1.31 | 1.49 ± 1.33 | 0.116 | 1.03 ± 1.07 | 1.60 ± 1.10 | 0.011 |
Number of high-quality cleavage embryos | 0.78 ± 1.19 | 1.32 ± 1.31 | 0.043 | 0.67 ± 0.92 | 1.23 ± 1.07 | 0.009 |
