Table 3 Comparison of average dose-volume parameters between perfect and imperfect implantatoin (Mean ± SD). Dates were obtained from 2 and 3D plan in these patients with uniform prescription of 6 Gy.

A. Dose volume effects of deviation of inadequate implantation (n = 12)

 VOI (cm³)

38.86 ± 9.93

38.86 ± 9.93

35.95 ± 9.82

35.95 ± 9.82

2.91 ± 7.06

2.91 ± 7.06

 CTV_ref (cm³)

34.96 ± 8.94

29.94 ± 10.60

32.38 ± 8.85

33.79 ± 10.25

2.6 ± 6.35

− 3.85 ± 9.32

 V_ref (cm³)

93.4 ± 31.43

70.97 ± 15.95

39.23 ± 10.55

83.63 ± 22.08

54.17 ± 31.71*

− 12.67 ± 24.27

 COIN

0.37 ± 0.15

0.33 ± 0.12

0.74 ± 0.05

0.38 ± 0.08

− 0.37 ± 0.15*

− 0.05 ± 0.14

 D_2cc bladder (cGy)

624.75 ± 173.28

486.94 ± 83.60

346.05 ± 42.19

483.93 ± 125.41

278.7 ± 177.59*

3.01 ± 143.93

 D_2cc rectum (cGy)

558.32 ± 128.16

400.37 ± 110.91

319.79 ± 58.27

475.34 ± 107.34

238.53 ± 130.84*

− 74.97 ± 133.60

 D_2cc sigmoid colon (cGy)

254.5 ± 164.43

199.94 ± 113.48

146.82 ± 83.16

247.68 ± 91.10

107.68 ± 165.36*

− 47.74 ± 131.86

 D_2cc small intestine (cGy)

477.13 ± 257.12

407.68 ± 129.11

257.53 ± 106.07

468.65 ± 226.35

219.61 ± 207.87*

− 60.97 ± 243.40

B. Dose volume effects of deviation of anterior wall perforation (n = 11)

 VOI (cm³)

36.01 ± 10.91

36.01 ± 10.91

36.17 ± 12.86

36.17 ± 12.86

− 0.16 ± 5.73

− 0.16 ± 5.73

 CTV_ref (cm³)

32.42 ± 9.82

28.64 ± 8.13

32.38 ± 11.62

35.15 ± 12.06

0.03 ± 5.24

− 6.51 ± 8.38*

 V_ref (cm³)

120.46 ± 84.16

88.95 ± 14.56

39.99 ± 14.28

92.65 ± 14.28

80.47 ± 84.76*

− 3.70 ± 18.64

 COIN

0.34 ± 0.17

0.27 ± 0.92

0.72 ± 0.06

0.37 ± 0.12

− 0.38 ± 0.16*

− 0.11 ± 0.12*

 D_2cc bladder (cGy)

736.26 ± 324.70

551.56 ± 87.13

368.41 ± 57.65

584.17 ± 97.82

367.85 ± 319.50*

− 32.60 ± 141.60

 D_2cc rectum (cGy)

604.28 ± 370.80

429.91 ± 132.52

286.9 ± 56.96

451.48 ± 132.50

317.38 ± 384.26*

− 21.57 ± 199.31

 D_2cc sigmoid colon (cGy)

247.12 ± 140.96

197.87 ± 69.80

179.14 ± 97.71

374.59 ± 198.72

67.99 ± 140.42

− 176.72 ± 163.96*

 D_2cc small intestine (cGy)

575.38 ± 499.20

523.82 ± 189.73

184.09 ± 89.29

385.5 ± 154.82

391.29 ± 458.63*

138.27 ± 145.26*

C. Dose volume effects of deviation of posterior wall perforation (n = 9)

 VOI (cm³)

29.87 ± 12.77

29.87 ± 12.77

30.35 ± 13.36

30.35 ± 13.36

− 0.48 ± 0.97

− 0.48 ± 0.97

 CTV_ref (cm³)

26.89 ± 11.50

25.19 ± 7.28

27.35 ± 12.03

29.94 ± 12.770

− 0.45 ± 0.87

− 4.75 ± 6.47

 V_ref (cm³)

79.06 ± 85.37

75.16 ± 15.01

33.21 ± 16.16

82.93 ± 15.50

45.86 ± 70.39

− 7.77 ± 12.46

 COIN

0.43 ± 0.15

0.29 ± 0.05

0.75 ± 0.07

0.35 ± 0.10

− 0.32 ± 0.16*

− 0.06 ± 0.13

 D_2cc bladder (cGy)

520.85 ± 222.64

558.08 ± 90.32

336.61 ± 45.59

602.54 ± 120.54

184.23 ± 234.71*

− 44.46 ± 120.39

 D_2cc rectum (cGy)

535.95 ± 231.25

597.53 ± 132.98

277.56 ± 63.59

488.74 ± 81.41

258.38 ± 181.37*

108.79 ± 125.43*

 D_2cc sigmoid colon (cGy)

394.27 ± 524.42

382.51 ± 99.44

167.51 ± 99.32

317.27 ± 118.47

226.76 ± 437.72

65.24 ± 88.84

 D_2cc small intestine (cGy)

420.83 ± 421.96

408.1 ± 147.27

173.93 ± 45.94

360.75 ± 130.13

246.9 ± 420.21

47.34 ± 209.52

D. Dose volume effects of deviation of fundus perforation (n = 6)

 VOI (cm³)

22.94 ± 7.17

22.94 ± 7.17

22.39 ± 6.59

22.39 ± 6.59

0.56 ± 2.31

0.56 ± 2.31

 CTV_ref (cm³)

19.91 ± 6.39

20.87 ± 6.81

20.42 ± 5.64

22.17 ± 6.52

− 0.52 ± 1.09

− 1.3 ± 1.39

 V_ref (cm³)

32.82 ± 17.05

73.06 ± 17.58

23.67 ± 5.20

64.36 ± 15.25

9.15 ± 12.10

8.7 ± 6.1*

 COIN

0.57 ± 0.17

0.26 ± 0.05

0.78 ± 0.05

0.34 ± 0.04

− 0.21 ± 0.16*

− 0.08 ± 0.04*

 D_2cc bladder (cGy)

365.72 ± 94.09

527.41 ± 129.07

312.7 ± 62.19

564.89 ± 127.70

53.06 ± 77.72

− 37.49 ± 126.3

 D_2cc rectum (cGy)

305.02 ± 74.67

477.52 ± 191.24

221.03 ± 47.75

379.5 ± 125.64

83.99 ± 92.33

98.02 ± 248.3

 D_2cc sigmoid colon (cGy)

245.4 ± 194.04

470.65 ± 255.65

87.28 ± 88.50

187.02 ± 179.92

158.13 ± 131.95*

283.63 ± 168.81*

 D_2cc small intestine (cGy)

262.56 ± 88.12

553.04 ± 105.29

213.45 ± 85.12

511.47 ± 132.21

49.11 ± 77.78

41.57 ± 207.48