Table 6 Correlations between the colloidal dispersion/suspension properties and the ODBF and CBD-ODF.
From: Exploring the interconnected properties of cannabidiol suspensions and orodispersible films
Formulation/parameters/codes | Formulation/parameters/codes | |||||||
---|---|---|---|---|---|---|---|---|
Uniformity of mass | Thickness | Adhesivity | Folding endurance | pH | Disintegration: pharmacopeial method | Disintegration: slide frame method | Thickness-normalized tensile strength | |
ODBF1 | ||||||||
DB1Conductivity | 0.32 | 0.27 | 0.97 | − 0.10 | − 0.75 | − 0.94 | − 0.94 | 0.68 |
DB1pH | 1 | − 0.55 | 0.07 | − 0.96 | − 0.5 | 0.50 | 0.50 | 0.60 |
DB1viscosity | − 0.86 | 0.86 | 0.00 | 0.86 | 0.0 | − 0.86 | − 0.86 | 0.00 |
ODBF2 | ||||||||
DB2Conductivity | − 0.74 | − 0.43 | 0.96 | − 0.81 | − 0.95 | − 0.62 | − 0.45 | − 0.64 |
DB2pH | − | 0.86 | − 0.86 | 0.86 | 0.86 | 0.00 | 0.86 | 0.00 |
DB2viscosity | − | 1.00 | − 0.95 | 0.85 | 0.93 | 0.57 | 0.50 | 0.59 |
CBD-ODF1 | ||||||||
DCBD1Conductivity | 0.07 | 0.43 | − 0.86 | − 0.50 | 0.50 | − 0.86 | 0.00 | − 1.00 |
DCBD1pH | 0.67 | − 0.12 | 0.00 | 0.22 | − 0.27 | 0.00 | 0.86 | 0.98 |
DCBD1viscosity | − 0.47 | − 0.97 | 0.00 | 0.99 | − 0.81 | 0.00 | 0.87 | 0.52 |
CBD-ODF2 | ||||||||
DCBD2Conductivity | 0.53 | − 0.50 | 0.34 | 0.34 | 0.20 | 0.08 | 0.00 | 0.35 |
DCBD2pH | 0.86 | 0.00 | 0.86 | 0.0 | 0.00 | 0.00 | − 0.50 | 0.0 |
DCBD2viscosity | − 0.95 | − 0.50 | − 0.99 | − 0.53 | − 0.62 | − 0.82 | 0.00 | − 0.51 |