Table 2 Signal strength for drug-Induced photosensitivity at the top ROR strength drugs in FAERS.
Rank* | Drug name | Drug category | Count (N) | ROR(95%CI) |
|---|---|---|---|---|
1 | Lamotrigine | Psychoanaleptics | 211 | 360.80(314.85,413.46) |
2 | Vemurafenib | Antineoplastic agents | 659 | 68.56(63.26,74.30) |
3 | Simeprevir | Antivirals | 164 | 42.61(36.41,49.87) |
4 | Voriconazole | Antibacterials | 410 | 32.57(29.49,35.98) |
5 | Rubraca | Antineoplastic agents | 226 | 25.80(22.59,29.48) |
6 | Pirfenidone | Immunosuppressants | 896 | 23.79(22.23,25.46) |
7 | Sumatriptan | Psychoanaleptics | 208 | 23.73(20.66,27.25) |
8 | Niraparib | Antineoplastic agents | 384 | 18.68(16.87,20.68) |
9 | Doxycycline | Antibacterials | 269 | 18.36(16.26,20.74) |
10 | Terbinafine | Antifungals | 74 | 8.62(6.85,10.84) |
11 | Ciprofloxacin | Antibacterials | 268 | 7.21(6.39,8.14) |
12 | Amiodarone | Cardiovascular system | 127 | 6.58(5.52,7.84) |
13 | Levofloxacin | Antibacterials | 138 | 3.61(3.05,4.27) |
14 | Isotretinoin | Anti-acne preparations | 152 | 3.55(3.02,4.16) |
15 | Omeprazole | Proton pump inhibitors | 90 | 3.66(2.98,4.51) |
16 | Aavobenzone\homosalate\octisalate\octocrylene(\oxybenzone) | Emollients and protectives | 378 | 2.80(2.48,3.17) |
17 | Paroxetine | Psychoanaleptics | 119 | 2.88(2.40,3.45) |
18 | Peginterferon alfa-2a | Interferons | 101 | 2.80(2.30,3.41) |
19 | Adapalene | Anti-acne preparations | 442 | 2.20(2.00,2.41) |
20 | Amlodipine | Cardiovascular system | 112 | 2.16(1.79,2.60) |
21 | Methotrexate# | Antineoplastic agents | 259 | 1.97(1.74,2.23) |
22 | Sertraline | Psychoanaleptics | 113 | 2.08(1.73,2.51) |
23 | Dupilumab | Monoclonal antibodies | 435 | 1.83(1.67,2.02) |
24 | Omalizumab | Monoclonal antibodies | 97 | 1.81(1.48,2.21) |
25 | Duloxetine | Psychoanaleptics | 104 | 1.80(1.48,2.18) |
26 | Venlafaxine | Psychoanaleptics | 77 | 1.77(1.42,2.22) |
27 | Rosuvastatin | HMG CoA reductase inhibitors | 78 | 1.62(1.30,2.03) |
28 | Fingolimod | Immunosuppressants | 134 | 1.48(1.25,1.76) |
29 | Secukinumab | Monoclonal antibodies | 186 | 1.31(1.14,1.52) |
30 | Adalimumab | Monoclonal antibodies | 807 | 1.19(1.11,1.28) |
31 | Certolizumab pegol | Monoclonal antibodies | 106 | 1.31(1.09,1.59) |
32 | Tocilizumab | Monoclonal antibodies | 72 | 1.29(1.02,1.63) |
33 | Atorvastatin | HMG CoA reductase inhibitors | 108 | 1.20(1.00,1.45) |
