Fig. 3
From: Serum metabolic profiling in rheumatic heart disease and degenerative aortic stenosis

Profiling of the important metabolites detected and altered in AS patients compared to controls. (a) The detected perturbations of phosphatidic acid. (b) Changes in taurine between AS patients and controls. (c) Exploration of the pathways associated with the metabolites detected in RHD, AS, and control samples showing the percentage coverage of the detected significant metabolites against the total metabolites within a KEGG pathway (for all the plots, control samples n = 16, AS samples n = 9; *raw p value < 0.05; **raw p value < 0.01). (AS aortic stenosis, PA phosphatidic acid, RHD-HC rheumatic heart disease vs. healthy controls, AS-HC aortic stenosis vs. healthy controls, RHD-AS rheumatic heart disease vs. aortic stenosis).