Fig. 6 | Scientific Reports

Fig. 6

From: LZTS2 methylation as a potential diagnostic and prognostic marker in LIHC and STAD: Evidence from bioinformatics and in vitro analyses

Fig. 6

Gene expression and methylation analysis of the LZTS2 gene in various cell lines. (A) qRT-PCR analysis of LZTS2 gene expression across a panel of cell lines: STAD: GES-1 (normal gastric cells), AGS, MKN7; LIHC: MIHA (normal liver cells), 97H, and LM3. Gene expression levels were normalized to the internal reference gene, and results are presented as mean ± standard deviation (SD) from three independent biological replicates. Statistical significance was assessed by one-way ANOVA, with p < 0.05 considered statistically significant. (B) Methylation conversion rates of the LZTS2 gene in the same set of cell lines, measured using bisulfite sequencing. Methylation levels are expressed as the percentage of methylated cytosines. Data are presented as mean ± SD, with significant differences between groups indicated by p < 0.05.

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