Fig. 2
From: The function of PCSK9 in doxorubicin-induced cardiotoxicity and its underlying mechanism
The expression of PCSK9 protein in myocardial tissue of mice was up-regulated after DOX treatment, and PCSK9 inhibitor improved DIC. A WB images of PCSK9 protein expression in cardiac tissue of both groups of mice (n = 8). B Gray scale scanning analysis of PCSK9/GAPDH protein expression (n = 8). C Show the survival rate over 12 days (n = 10). D Bar graph of survival rate (n = 10). E Body weight of the three groups of mice over 12 days (n = 10). F Images of the heart size of three groups of mice (n = 10). G Heart weight (n = 10). H Heart weight to body weight ratio (n = 10). Data are presented as mean ± SD, *P < 0.05, ***P < 0.001, vs. Control group, #P < 0.05, ##P < 0.01, ###P < 0.001 vs. DOX group.
