Fig. 2
Network showing the inborn errors of immunity category as classified by International Union of Immunological Societies expert committee7 and symptoms in 92 children with inborn errors of immunity. Red nodes represent inborn error of immunity(IEI) category, while blue nodes represent symptoms. The larger nodes characterize the increased degree of a node in the network (increased number of connections to other nodes). Supplementary file includes the symptom frequency. Some IEI categories were shortened to improve reading of the graph, as follows: Combined immunodeficiencies—Combined immunodeficiencies with associated or syndromic features; Defects of phagocyte—Congenital defects of phagocyte number or function; Immune dysregulation—Diseases of immune dysregulation; Cellular and humoral IEI—Immunodeficiencies affecting cellular and humoral immunity; Phenocopies of IEI- Phenocopies of inborn errors of immunity; Antibody deficiencies—Predominantly antibody deficiencies.
