Fig. 2 | Scientific Reports

Fig. 2

From: NOX4 as an emerging prognostic and immunological biomarker across pan-cancer analyses

Fig. 2

Expression levels of NOX4 in pan-cancer. (A) TIMER2.0 displays the expression of NOX4 across TCGA tumors and corresponding normal tissues. (B) The expression of NOX4 in tumor and normal tissues, as shown on the UALCAN website, which provides protein level data for NOX4 across various tumor types. (C) RT-PCR analysis of NOX4 expression in different tumor types, indicating potential variations in NOX4 regulation across cancers. (D) Expression of NOX4 protein in KIRC provided by the CPTAC website. (E) NOX4 expression through unsupervised cluster analysis for pan-cancer subtypes (S1 to S11) of different tumor types in CPTAC. (F) Single-cell map of KIRC from the GSE159115 dataset. (G) NOX4 expression in KIRC’s single-cell map. (H) Differential expression analysis of NOX4 in KIRC’s single-cell map, revealing significant upregulation in specific cell populations. (I) Hematoxylin and eosin staining of adjacent normal tissue and KIRC. (J) Immunohistochemical staining of NOX4 in KIRC and adjacent normal tissue. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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