Fig. 7 | Scientific Reports

Fig. 7

From: Analysis of human factor H-related gene and protein expressed in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation

Fig. 7

Correlations between FHR3, X-ray erosion, and X-ray joint space narrowing from the STRAP clinical trial. A No correlation between FHR3 mRNA expression and X-ray erosion in RA patients. B No correlation between FHR3 mRNA expression and X-ray joint space narrowing in RA patients. C No correlation between FH mRNA expression and X-ray erosion in RA patients. D A negative and significant correlation between FH mRNA expression and X-ray joint space narrowing in RA patients. X-ray erosion = radiographically (X-ray) demonstrable bone erosion in RA. X-ray joint space narrowing = radiographs (X-ray) used to manually measure and quantify joint space to determine the severity of RA. STRAP n = 208. Correlation = r and *p < 0.05 are considered significant.

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